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15. TYPICAL FORMS OF PATHOLOGY OF THE WHITE BLOOD CELL SYSTEM. LEUKOCYTOSIS AND LEUCOPENIA. LEUKEMOID REACTIONS

I. Choose the types of leukocytes normally present in the peripheral blood of healthy people.

1. Neutrophils, monocytes, lymphocytes, eosinophils, basophils.

2. Neutrophils, promonocytes, lymphocytes, eosinophils, basophils.

3. Neutrophils, promyelocytes, lymphocytes, eosinophils, basophils.

4. Neutrophils, metamyelocytes, lymphocytes, eosinophils, basophils.

II. Leukocytosis may result from the following:

1. Increased release from the storage pool in the marrow.

2. Demargination of neutrophils.

3. Decreased extravasation of leukocytes into tissues.

4. Expansion of marrow leukocyte precursor pool.

5. Splenomegaly.

6. Increased peripheral use of leukocytes.

7. Suppression of myeloid stem cells.

III. Leukopenia may result from the following:

1. Insufficiency of vitamin B12.

2. Splenomegaly.

3. Overwhelming bacterial, fungal or rickettsial infections.

4. Aplastic anemia.

5. Strenuous physical exercise.

6. Antimetabolites used in cancer treatment.

7. Tissue necrosis such as myocardial infarction or burns.

8. Increased production of erythropoietin.

IV. Stimulation of myeloid line in the bone marrow is associated with the following changes in the peripheral blood:

1. Nuclear shift to the left.

2. Nuclear shift to the right.

3. Increased number of leukocytes in the blood.

4. Increased number of reticulocytes.

5. Increased hematocrit.

V. Redistribution of leukocytes in the peripheral blood in leukocytosis is caused by:

1. Increased release of leukocytes from the marrow storage pool.

2. Expansion of the marrow precursor pool.

3. An increase in the peripheral blood marginating pool.

4. An increase in the peripheral blood circulating pool.

5. Decreased extravasation of leukocytes into tissues.

VI. Mechanisms of the regenerative leukocytosis are:

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