I. Choose manifestations of acute leukemias demonstrating their neoplastic nature.
1. Increased rate of blast cells division.
2. Infiltrative growth.
3. Intoxication of organism.
4. The ability to metastasize.
5. Morphological abnormalities of leukemic cells.
6. Hyperalbuminemia.
7. Block of differentiation.
II. Which of the following factors may cause leukemia?
1. Smoking.
2. Aberration of the first chromosome pair.
3. Polycyclic hydrocarbons.
4. Ionizing radiation.
5. Epstein-Barr virus.
6. Ultraviolet rays.
III. The most common causes of death in leukemias are:
1. Derangements of metabolism.
2. Hemorrhage into life-important organs.
3. Sepsis.
4. Cachexia.
5. Anemia.
6. Pneumonia.
IV. Which of the following findings in the peripheral blood characterize myeloid leukemoid reaction?
1. Severe neutrophil leukocytosis with nuclear shift to the left (up to promyelocytes and myeloblasts).
2. Hiatus leukemicus.
3. The presence of the toxicity granules in myeloid cells.
4. The presence of eosinophilic-basophilic association.
5. The presence of lymphoblasts.
6. The presence of myelocytes.
7. The presence of promyelocytes.
8. Increased phagocytic activity of leukocytes.
V. What pattern of cells in the peripheral blood is typical for chronic myeloid leukemia?
1. Myeloblasts, promyelocytes, myelocytes, metamyelocytes, mature neutrophils, eosinophils, basophils.
2. Myeloblasts, promyelocytes, mature neutrophils, eosinophils, basophils.
3. Myeloblasts, metamyelocytes, mature neutrophils, eosinophils, basophils.