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JANNDICE

Parameters of bilirubin pigments metabolism

Peripheral blood: Total bilirubin <1.3 mg/dl. Unconjugated bilirubin <1.0 mg/dl. Conjugated bilirubin <0.3 mg/dl. Urobilinogen - not detected. Stercobilinogen - detected.

Define changes in the bile pigments level and composition in biological fluids and explain possible causes and mechanisms of their development. Make a general conclusion on the given data.

Blood

Urine

Stool

N 194*

Total bilirubine

2.6 mg/dl

-

-

Conjugated bilirubine

0.15 mg/dl

Not found

-

Urobilinogen

+

+

+

Stercobilinogen

Increased

Increased

Increased

Cholic acids

Not found

Not found

-

N 195

Total bilirubine

2.4 mg/dl

-

-

Conjugated bilirubine

1.4 mg/dl

+

-

Urobilinogen

Trace amounts

Trace amounts

-

Stercobilinogen

Trace amounts

Trace amounts

Very low

Cholic acids

+

+

-

Alanine

aminotransferase

Increased

-

-

Aspartate aminotransferase

Increased

-

-

N 196

Total bilirubine

1.5 mg/dl

-

-

Conjugated bilirubine

0.5 mg/dl

Trace amounts

-

Urobilinogen

+

+

+

Stercobilinogen

Norm

Norm

-

Cholic acids

Not found

Not found

-

Blood Urine Stool

N 197

Total bilirubine

2.43 mg/dl

-

-

Conjugated bilirubine

0.35 mg/dl

Trace amounts

-

Urobilinogen

Not found

Not found

-

Stercobilinogen

Decreased

Decreased

Decreased

Cholic acids

+

+

-

Alanine

aminotansferase

Very high

-

-

Aspartate aminotransferase

Very high

-

-

N 198

Total bilirubine

2.4 mg/dl

-

-

Conjugated bilirubine

1.4 mg/dl

+

-

Urobilinogen

-

-

-

Stercobilinogen

-

-

-

Cholic acids

+

+

+

Alanine

aminotransferase

Norm

-

-

Aspartate aminotransferase

Norm

-

-

N 199

Total bilirubine

1.8 mg/dl

-

-

Conjugated bilirubine

0.2 mg/dl

+

-

Urobilinogen

-

-

-

Stercobilinogen

Norm

Norm

Norm

Cholic acids

-

-

-

N 200

Total bilirubine

3.5 mg/dl

-

-

Conjugated bilirubine

2.1 mg/dl

+

-

Urobilinogen

-

-

-

Stercobilinogen

Trace amounts

Trace amounts

Decreased

Cholic acids

+

+

-

Alanine

aminotransferase

Increased

-

-

Blood

Urine

Stool

N 201

Total bilirubine

4.4 mg/dl

-

-

Conjugated bilirubine

0.35 mg/dl

Trace amounts

-

Urobilinogen

+

+

-

Stercobilinogen

Increased

Increased

Norm

Cholic acids

-

-

-

Alanine

aminotransferase

Increased

-

-

N 202

Total bilirubine

2.1 mg/dl

-

-

Conjugated bilirubine

0.2 mg/dl

-

-

Urobilinogen

-

-

-

Stercobilinogen

Increased

Increased

Increased

Cholic acids

-

-

-

Alanine

aminotransferase

norm

-

-

N 203

Total bilirubine

3.6 mg/dl

-

-

Conjugated bilirubine

2.5 mg/dl

+

-

Urobilinogen

-

-

-

Stercobilinogen

-

-

Trace amount

Cholic acids

-

-

-

Alanine

aminotransferase

Norm

-

-

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